Abstract:[Objective]To compare the influence between modified Jaslow technique combined with single Z-Cage and PLIF on spine-pelvic sagittal parameters in isthmic spondylolisthesis patients.[Methods]From December 2014 to March 2017,87 patients with L5/S1 single-segmental isthmic spondylolisthesis were included,of which 49 patients were treated with modified Jaslow technique;38 patients were treated with PLIF.K-Means cluster analysis was used to classify patients into balanced and unbalanced types based on the relative ratios of PT and SS.Some indicators were recorded to evaluate the treatment of surgery in both groups.[Results]①The operation time,intraoperative blood loss and postoperative drainage volume of the Jaslow group were significantly lower than those of the PLIF group(p<0.05).The JOA,VAS and ODI of the two surgical groups were significantly improved(p<0.05)②In balanced pelvic group,there was no statistical difference between the two groups of △SP,△SA,△LL,△PT.The CS in Jaslow group was 1.15±0.53mm,which was lower than that in PLIF group(1.54±0.59mm)(p>0.05),but there was no statistical difference.The SR in Jaslow group was 6.3%,which was significantly lower than that in PLIF group (29.0%,p<0.05).③In unbalanced pelvic group,△SP,△SA,△LL,△PT in Jaslow group were significantly greater than those in PLIF group(p<0.05);CS and SR in Jaslow group were 1.15±0.53mm and 6.3%,significantly lower than that in PLIF group(1.54±0.59mm,29.0%,p<0.05).[Conclusion]For the isthmic spondylolisthesis,modified Jaslow technique and PLIF can also obtain satisfactory clinical results,restore the lumbar lordosis,and the lumbar-pelvic sagittal balance.For severe lumbar spondylolisthesis patients with unbalanced pelvic,the modified Jaslow technique can also reduce slip percentage,slip angle and pelvic tilt angle,and restore lumbar lordosis and sagittal balance more effectively.