[Objective] To introduce the design and preliminary application results of multi-purpose shield in total knee arthroplasty(TKA). [Methods] The multi-purpose shield was comprised with shield plate connected with each other, a handle and a negative pressuregetter. The shield plate was provided with a circular transparent window, a circular transparent window channel and a rectangular transpar-ent window. The rectangular transparent window was arranged in the middle of the top edge of the baffle, while the circular transparent win-dow was arranged on one side of the geometric center of the shield. The handle was connected with the lower part of the shield, where a nega-tive pressure getter connected with the opening in the middle part of the shield plate to form an suction port. The rear end opening was con-nected to an external negative pressure suction pipe to suck out the blood and debris near the shield plate or attached to the surface of theplate. [Results] The multi-purpose shield was applied in TKA in 86 patients, which effectively shielded the spattered blood and bone frag-ments, greatly reduced the surgical infection rate, and effectively protected medical staff to prevent blood-borne occupational exposure. All86 patients had the operation performed successfully, with surgical incision healed well. All of them got knee function recovered well, withno serious complications such as infection occurred during follow-up. [Conclusion] This multi-purpose shield blocks and absorbs the pollut-ants such as blood and bone fragments spattered during TKA, reduces the infection rate, and reduces the pollution and injury to medical staff.