[Objective] To evaluate the clinical outcomes of metacarpal condylar locking plate for fixation of zone I. fracture of the fifth metatarsal. [Methods] A retrospective study was done on 19 patients who received metacarpal condylar locking plate for fixation of zone I. fracture of the fifth metatarsal from June 2017 to June 2020. The clinical and imaging consequences were evaluated. [Results] All patients had operation performed smoothly with the operation time of (51.6±9.7)min, incision length of (3.7±0.8)cm, and intraoperative blood loss of (15.5±2.4)ml. The patients were followed up for (10.9±2.8) months on a mean, and resumed full weight- bearing activities in (10.2±2.4) weeks. Compared with those preoperatively, the VAS score at 6 months after surgery and the last follow-up significantly decreased [(2.5± 1.2), (1.7±1.2), (1.0±0.6), P＜0.05], while the AOFAS score significantly increased [(74.2±7.8), (83.2±8.3), (92.1±8.5), P＜0.05]. Among the 19 patients, the quality of fracture reduction was excellent in 16 cases and good in 3 cases, and all patients got fractures healed in 6 months. [Conclusion] Metacarpal condylar locking plate used for fixation of zone I fracture of the fifth metatarsal base is stable and achieves satisfac- tory clinical outcome.