[Objective] To search the morphological characteristics of lumbar pedicle in Tibetan adults by comparison of the morphologi- cal differences of lumbar pedicle between Tibetan and Han ethnic groups and between male and female to provide reliable anatomical data for lumbar pedicle screws fixation in Tibetan patients. [Methods] A total of 200 persons, including 100 Tibetan and 100 Han with 50 male and 50 female in each ethnic group were randomly selected based on the inclusion criteria. The pedicle width, axis length, sagittal diameter, cross-sectional angle and sagittal angle from L₁ to L₅ vertebrae were measured by CT examination, and compared between ethnic groups and gender groups. [Results] The lumbar pedicle width and cross-sectional angle increased from L₁ to L₅ in the 200 subjects (P＜0.05) , while the sagittal diameter of the pedicle decreased gradually from L₁ to L₅ (P＜0.05) , the axis length of lumbar pedicle was of the maximal value at L₃ levels (P＜0.05) , the lumbar pedicle sagittal angle was generally decreased up-down (P＜0.05) . The data in terms of some lumbar pedicle di- ameters were significantly different between Tibetan and Han ethnic groups, in addition, the male was significantly greater in terms of the width, axis length and sagittal diameter of lumbar than the female (P＜0.05) . [Conclusion] There are differences in the measurement of lum- bar pedicle morphology among different races and genders. Therefore, ethnic and gender differences should be considered in the selection of screw placement angle and screw type during lumbar pedicle internal fixation. In other words, it may be necessary to perform CT and other examinations on the involved vertebrae before operation.