[Objective] To compare the clinical efficacy of robot-assisted (RA) versus traditional freehand (FH) percutaneous screw fix- ation for acetabular fractures. [Methods] A retrospective study was performed on 24 patients who had acetabular anterior column fracture fixed by percutaneous screws in our hospital from January 2018 to September 2021. According to the preoperative doctor-patient communi- cation, 12 patients received RA technique, while the remaining 12 patients underwent the traditional FH technique. The perioperative, fol- low- up and imaging consequences were compared between the two groups. [Results] All the patients in both groups had operation per- formed smoothly without neurovascular injury and other serious complications. Although there was no a significant difference in operation time between the two groups (P＞0.05) , the RA group proved significantly superior to the FH group in terms of screw placement time [(32.5± 7.2) min vs (57.6±11.9) min, P＜0.05] , guide pin adjustment times [(0.5±0.5) times vs (6.8±1.1) times, P＜0.05] , radiation exposure duration [(23.0± 7.6) sec vs (78.5 ±13.7) sec, P＜0.05] , intraoperative fluoroscopy times [(14.9±4.0) times vs (52.9±8.6) times, P＜0.05] and intraoper- ative blood loss [(32.0±9.0) ml vs (74.8±19.5) ml, P＜0.05] . However, there were no significant differences in incision healing grade and hos- pital stay between the two groups (P＞0.05) . All of them in both groups were followed up for more than 12 months, and there were no signifi- cant differences in time to return to walking and full weight-bearing activity between the two groups (P＞0.05) . As time went the VAS score for pain significantly decreased (P＜0.05) , while Majeed score significantly increased in both groups (P＜0.05) , which proved not statistical- ly significant between the two groups at any time points accordingly (P＞0.05) . Radiographically, no significant changes in Matta rating or implant position were observed in both groups at the last follow-up compared to those immediately postoperatively (P＞0.05) . In addition, there was no significant difference in the fracture healing time on images between the two groups (P＞0.05) . [Conclusion] Compared with the traditional freehand technique, the robot-assisted percutaneous anterograde acetabular screw fixation is more accurate, with less intra- operative radiation exposure, less tissue damage, and more stable clinical efficacy.