[Objective] To explore the clinical outcomes of one-stage total hip arthroplasty (THA) for high-displacement dislocation of the hip in adults. [Methods] From May 2017 to March 2021, 13 patients (17 hips) underwent THA in our department for high-displacement dislocation of the hip due to congenital dislocation of the hip in 7 cases (11 hips) , previous pyogenic hip osteoarthropathy in 2 cases, and un- reduced traumatic posterior dislocation of the hip in 4 cases. [Results] All patients had THA performed successfully with well incision heal- ing without infection and deep vein thrombosis, despite of the fact that temporary femoral nerve palsy in 1 case and re-dislocation in 2 cases were found, which were treated correspondingly without serious consequences. At the latest follow up lasted for (33.1±15.6) month the VAS score for pain significantly decreased (P＜0.05) , while the hip flexion-extension range of motion (ROM) , external-internal rotation ROM and Harris score significantly increased compared with those preoperatively (P＜0.05) . In term of radiographic evaluation, the leg length discrep- ancy and position of rotate centers significantly improved at the latest follow up compared with those preoperatively (P＜0.05) , with osteoto- my healed from 4 to 8 months postoperatively. [Conclusion] The one-stage THA used for high-displacement dislocation of the hip does achieve satisfactory mid-term clinical outcomes.