富血小板血浆促进半月板修复的研究进展
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甘肃省人民医院骨二科

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中图分类号:

R684

基金项目:

甘肃省青年科技基金计划


Research progress of platelet-rich plasma in promoting meniscus repair
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Affiliation:

The Second Department of Orthopaedics, Gansu Provincial People’s Hospital

Fund Project:

Gansu Youth Science and Technology Fund Plan

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    摘要:

    富血小板血浆(platelet-rich plasma, PRP)是从静脉血液中分离提取出来的一种含有丰富血小板和生长因子的血液衍生产品,富含多种生长因子和血小板,PRP通过促进半月板细胞再生、增加胶原蛋白合成、调节损伤半月板内部微环境等方式,参与延缓或修复半月板损伤和减少膝关节疼痛。本文旨在总结半月板损伤的特点、PRP的制备和分类、PRP 修复半月板损伤的作用机制及在半月板损伤中应用的现状与不足,提出今后PRP在促进半月板修复的发展方向,以便更好地指导临床实践。

    Abstract:

    Platelet-rich plasma ( PRP ) is a blood-derived product rich in platelets and growth factors isolated from venous blood. It is rich in a variety of growth factors and platelets. PRP is involved in delaying or repairing meniscus injury and reducing knee pain by promoting meniscus cell regeneration, increasing collagen synthesis, and regulating the internal microenvironment of the injured meniscus. The purpose of this paper is to summarize the characteristics of meniscus injury, the preparation and classification of PRP, the mechanism of PRP in repairing meniscus injury and the current situation and shortcomings of its application in meniscus injury, and to put forward the development direction of PRP in promoting meniscus repair in the future, so as to better guide clinical practice.

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历史
  • 收稿日期:2023-06-18
  • 最后修改日期:2023-08-22
  • 录用日期:2023-11-01
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