Abstract:[Objective] To compare the early effects of robot ARTHROBOT-assisted total hip arthroplasty (rTHA) and traditional manual total hip arthroplasty (mTHA).[Methods] The clinical data of 58 patients who underwent THA in our hospital from April 2022 to November 2022 were collected retrospectively. According to the different operation methods, the patients were divided into two groups: rTHA group (n = 28) and mTHA group (n = 30). The perioperative period, follow-up and imaging data of the two groups were compared.[Results] The operation was successful in both groups, and no intraoperative complications were found. The operation time and the total length of incision in rTHA group were significantly longer than those in mTHA group(P < 0.05). There was no significant difference in intraoperative blood loss, wound healing grade and hospitalization time between the two groups(P > 0.05), but the treatment cost was higher in rTHA group(P < 0.05). There was no significant difference in complete weight-bearing time between the two groups (P > 0.05). During the follow-up period, the Harris score at 1 month and the last follow-up and the hip internal-external rotation ROM at 6 months after operation in the rTHA group were significantly higher than those in the mTHA group(P < 0.05). There was no significant difference in VAS score and hip extension-flexion ROM at 1 month, 6 months and the last follow-up, Harris score at 6 months after operation, and hip internal-external rotation ROM at 1 month and the last follow-up(P > 0.05). With the passage of time, the VAS score decreased significantly, while the Harris score, hip extension-flexion ROM and hip internal-external rotation ROM increased significantly in both groups(P < 0.05). The postoperative LLD, bilateral FOD difference, bilateral AOD difference and bilateral COD difference in the rTHA group were significantly lower than those in the mTHA group(P < 0.05), but there was no significant difference in AAA and AA between the two groups(P > 0.05). According to the standard of Lewinnek safe zone, the proportion of cases in rTHA group was significantly higher than that in mTHA group(P < 0.05). [Conclusion] Robotic ARTHROBOT-assisted total hip replacement makes prosthesis implantation more precise, and the proportion of acetabular cup placement in the safe zone is higher, which can better restore the hip offset of the affected hip, help reduce LLD, and achieve better results.