[Objective] To investigate the clinical outcomes of anatomical reconstruction of spinal canal after intraspinal tumor resec- tion. [Methods] From February 2013 to May 2017, 48 patients underwent anatomical reconstruction of spinal canal with central piece plate secondary to intraspinal tumor resection. The clinical and imaging findings were evaluated. [Results] All the patients had operation complet- ed smoothly without serious complications, and were followed up for (35.8±13.6) months on an average. The VAS and ODI scores significant- ly decreased (P＜0.05) , while the ASIA neurological function grade significantly improved over time (P＜0.05) . Radiographically, all patients got tumors removed completely with sufficient dural decompression at 1 week after operation. Three months after operation, the CT three-di- mensional reconstruction showed that the re-implanted lamina healed well, and the segment ROM and spinal canal area significantly in- creased after operation (P＜0.05) , whereas no spinal deformity, spinal instability or spondylolisthesis and tumor recurrence were found in anyone of them. [Conclusion] Anatomical reconstruction of the spinal canal with central piece plate after intraspinal tumor resection does maintain the volume of the spinal canal and the integrity of the spinal bone-ligament structure.