[Objective] To explore the clinical effect of bone transfer technique in the treatment of severe traumatic tibial defect.[Methods] The clinical data of 12 patients with severe traumatic tibial defect treated in our department from May 2018 to July 2022 were analyzed retrospectively. All patients were treated with bone transfer technique to treat severe traumatic tibial defect, and the perioperative and follow-up results were evaluated.[Results] All patients completed the operation successfully and there was no important nerve and vascular injury during the operation. The length of bone defect was (6.9 ±1.2) cm, the fixation time of external fixator was (606.3 ±55.2)d, and the bone healing index was (62.4 ±5.0) d/cm. The follow-up time was (26.3 ±7.5)months. HSS score, AOFAS score, knee extension-flexion ROM and ankle dorsal extension-metatarsal flexion ROM increased significantly with the increase of time(P < 0.05). In terms of imaging, with the increase of time, the length difference of bilateral tibia decreased significantly (P < 0.05), and the tibial force line was significantly corrected (P < 0.05). The bone defects and opposite interfaces of all patients healed.[Conclusion] Bone transfer is an effective method for the treatment of severe traumatic tibial defect. The application of bone transfer technology needs to design the treatment scheme of the interface in advance, which can effectively promote the healing of the interface.