Objective：The purpose of this study was to compare the application of two anchor techniques in the repair of anterior talofibular ligament under Arthroscopy. Methods：A retrospective analysis was performed on 88 patients who underwent arthroscopic repair of the anterior talofibular ligament using two types of anchors between January 2018 and January 2021. The perioperative period, follow-up data and imaging evaluation were compared between the two groups. Results：49 patients underwent repair with knotless anchors (non-knotted group) and 39 patients underwent repair with absorbable suture anchors (knotted group), with a follow-up period of at least 24 months. The knot irritation complications in the knotted group were significantly higher than those in the non-knotted group. At the last follow-up after surgery, there was a significant improvement in VAS score, AOFAS-AH score, and Karlsson Peterson score in both groups. There was no statistically significant difference in scores between the two groups (P>0.05). There was no statistically significant difference in ankle joint range of motion between the two groups during the last postoperative follow-up compared to before surgery (P>0.05); Compared with before surgery, at the last follow-up after surgery, both groups of patients showed significant improvement in the anterior drawer test (P<0.05), and there was no statistically significant difference between the two groups (P>0.05). Compared with before surgery, at the last follow-up after surgery, the distance of talus anterior displacement and talus varus angle on stress radiographs were significantly reduced in both groups compared to the healthy side (P<0.05), and there was no statistically significant difference between the two groups (P>0.05). Conclusion：The use of arthroscopic ATFL repair technique in the treatment of chronic ankle ligament injuries can restore stability and achieve good clinical results. Compared with the arthroscopic knot-tying group, the no-knotted group can obtain similar clinical results and has a lower incidence of complications, which is worthy of clinical recommendation.