Rotator cuff retear is a serious complication after arthroscopic rotator cuff repair, which impacts the quality of life of the pa- tients. There are many factors related to rotator cuff retear, such as age, hyperlipidemia, osteoporosis, etc., which have become hot and diffi- cult point of clinical practice in shoulder surgery at present. In order to find the related factors of rotator cuff retear, this paper reviewed the literature to find the most important single or multiple factors of rotator cuff retear, and to evaluate and improve the efficacy of rotator cuff re- pair.