[Objective] To determine whether the posterior stabilized (PS) prosthesis can obtain better clinical efficacy, kinematic function and knee stability than ultracongruent (UC) prosthesis. [Methods] PubMed, EMBASE, Cochrane Library, Wanfang, CNKI, and China Biology Medicine Disc database were searched for relevant studies on the use of PS and UC prosthesis in primary total knee arthroplasty (TKA). The search time limit was from the establishment of the database to December 2021. Two reviewers independently screened literature and extracted data. The quality of the studies was evaluated according to the Newcastle-Ottawa Scale (NOS) and the Cochrane risk of bias assessment tool. Review Manager 5.4 was used for meta-analysis. [Results] A total of 22 studies were included in this meta-analysis , including 11 randomized controlled trials, 9 retrospective studies, and 2 prospective studies. A total of 2904 knees were included. The results of meta-analysis showed that the femoral rollback[WMD=-5.20, 95% CI (-5.85, -4.54), p ＜0.001] and the maximal flexion [WMD= -2.27, 95% CI（-3.75, -0.79），p =0.003] in PS group were higher than UC group. The tibial sagittal laxity of PS group was significantly lower than UC group [WMD= 5.10，95% CI（3.45，6.76），p＜0.001]. There were no significant differences in function score, pain score, flexion contracture, range of motion and peak torque between the two groups. [Conclusions] In the primary TKA, the PS prosthesis has better kinematics and knee stability, and is still the best choice of posterior cruciate ligament replacement prosthesis.