Chinese medicines on postoperative reaction at early stage in elder rabbits // LU Hong-xiu, Zhang Jin , Yang Pei-ran, Sun Li,ZHANG Jian-xin. The Affiliate Hospital, Shandong University of Traditional Chinese Medicine, Jinan 250011, China Abstract: [Objective] To investigate the effect of high iliac fascia block (FICB) on delirium (POD) and rapid outcome after total hip arthroplasty in the elderly. [Methods] 140 patients with total hip arthroplasty were selected and randomly divided into observation group and control group with 70 patients in each group. Intraspinal anesthesia was selected for all operations. The observation group was given high FICB plus sufentanil intravenous analgesia (PCIA) immediately after operation, while the control group was given sufentanil PCIA immediately after operation. The VAS and BCS scores were recorded at 4, 8, 12, 24 and 48 hours after the operation; The effective press times of analgesia pump within 48 hours after operation, the total press times of 48 hours after operation, the recovery rate of analgesia, the adverse reactions related to analgesia, the Pittsburgh sleep quality (PSQI) score, the postoperative cognitive (MMSE) score, and the hip joint function recovery (Harris) score were recorded. [Results] The VAS score of the observer at 8h, 12h and 24h after operation was lower than that of the control group (P<0.05), while the BCS score was higher than that of the control group with significant difference; The first press time of PCIA, the total press times of 48 hours and the cases of analgesia relief were lower in the observation group (P<0.05); The MMSE score in the observation group was higher than that in the control group (P<0.05) and the PSQI score was lower than that in the control group (P<0.05) on the 1st and 3rd day after operation; Harris score in the observation group was higher than that in the control group on the first day after admission and the first day before discharge (P<0.05). [Conclusion] High FICB combined with sufentanil intravenous analgesia can effectively relieve pain after total hip replacement in the elderly, reduce the amount of sufentanil, improve postoperative comfort, improve sleep quality, thereby reducing the incidence of POD and promoting the rapid recovery of hip joint function.