下腰痛病患椎间盘退变程度与椎间盘高度量效关系的研究
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1.马鞍山市人民医院;2.安徽医科大学马鞍山临床学院

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2021年安徽省重点研究与开发项目(编号:202104j07020060);2022年度马鞍山市科技计划项目(编号:YL-2022-3)


Quantitative study on the correlation between the degree of degeneration of intervertebral discs and the height of intervertebral discs in patients with low back pain
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1.Maanshan People'2.'3.s Hospital;4.Anhui Medical University, Maanshan Clinical College Maanshan;5.Maanshan People&6.amp;7.#39;8.&9.马鞍山市人民医院

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    摘要:

    摘要:目的:研究下腰痛病患椎间盘退变程度与椎间盘高度的量效关系。方法:对2021年1月至2022年6月于我院脊柱骨科就诊的151例下腰痛病患行腰椎MRI检查,测量其椎间盘高度,利用Pfirrmann分级系统行腰骶椎间盘退变分级,通过F检验检测腰骶段各椎间盘不同退变等级的高度是否存在差异,并通过回归分析进一步量化这种差异的相关性。结果:在每一腰骶段,椎间盘退变程度与椎间盘高度呈负相关关系(P值均≤0.01),当排除1级及5级椎间盘退变时,结果保持不变(P值均≤0.01);为了进一步量化其相关性,在不同腰骶部水平测量其椎间高度,椎间盘退变等级每增加一级,在调整年龄,性别,体重指数后,椎间盘高度有所降低,差异均具有统计学意义(P值均≤0.01)。结论:本研究表明下腰痛患者椎间盘退变严重程度与椎间盘高度之间存在负量效关系,并证实了椎间盘高度可作为腰椎间盘退行性变程度的一种定量测量指标,具有一定的临床参考价值。

    Abstract:

    [Abstract] Objective: To investigate the quantitative relationship between the degree of disc degeneration and disc height in patients with lower back pain..Methods: From January 2021 to June 2022, 151 patients with lower back pain who attended our spinal orthopaedic department underwent MRI examination of the lumbar spine to measure their disc heights, and the Pfirrmann grading system was used to grade the lumbosacral disc degeneration. The F-test was used to determine whether there was a difference in the height of the discs at different levels of degeneration in the lumbosacral segment, and the correlation between this difference was further quantified by regression analysis.Results: At each lumbosacral segment, the degree of disc degeneration was negatively correlated with disc height (all p ≤ 0.01) and the results remained unchanged when grade 1 and grade 5 disc degeneration were excluded (all p ≤ 0.01); to further quantify the correlation, intervertebral disc height was measured at different lumbosacral levels and each increase in disc degeneration grade, after adjusting for age, gender and body mass index, resulted in a decrease in disc There was a decrease in height with each increasing level of disc degeneration, after adjustment for age, gender and body mass index. All differences were statistically significant (p-values ≤ 0.01). Conclusion: This study demonstrates a negative quantitative relationship between severity of disc degeneration and disc height in patients with lower back pain. It confirms that disc height can be used as a quantitative measure of the degree of lumbar disc degeneration and has clinical reference value.

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  • 收稿日期:2022-12-06
  • 最后修改日期:2022-12-06
  • 录用日期:2023-01-18
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