Abstract:[Abstract] Objective: To investigate the quantitative relationship between the degree of disc degeneration and disc height in patients with lower back pain..Methods: From January 2021 to June 2022, 151 patients with lower back pain who attended our spinal orthopaedic department underwent MRI examination of the lumbar spine to measure their disc heights, and the Pfirrmann grading system was used to grade the lumbosacral disc degeneration. The F-test was used to determine whether there was a difference in the height of the discs at different levels of degeneration in the lumbosacral segment, and the correlation between this difference was further quantified by regression analysis.Results: At each lumbosacral segment, the degree of disc degeneration was negatively correlated with disc height (all p ≤ 0.01) and the results remained unchanged when grade 1 and grade 5 disc degeneration were excluded (all p ≤ 0.01); to further quantify the correlation, intervertebral disc height was measured at different lumbosacral levels and each increase in disc degeneration grade, after adjusting for age, gender and body mass index, resulted in a decrease in disc There was a decrease in height with each increasing level of disc degeneration, after adjustment for age, gender and body mass index. All differences were statistically significant (p-values ≤ 0.01). Conclusion: This study demonstrates a negative quantitative relationship between severity of disc degeneration and disc height in patients with lower back pain. It confirms that disc height can be used as a quantitative measure of the degree of lumbar disc degeneration and has clinical reference value.