Primary malignant sternal tumors are rare, mostly sarcomas, and radical resection is the preferred treatment. With the application of 3D printed titanium alloy prosthesis in chest wall reconstruction, chest wall enlargement excision has been widely used in clinic. For upper sternal tumors, the sternoclavicular joint is usually excised to ensure a negative margin. There are few reports about the effect of sternoclavicular joint loss on the function of upper limb and whether the sternoclavicular joint can be reconstructed. A patient with manubrium sternal sarcoma was admitted to our hospital. The sternum and sternoclavicular joint were reconstructed by 3D printing technology, and good therapeutic effect was achieved after surgery. This paper makes a report on this case and summarizes the experience, and provides some reference for similar problems in the future.