[Objective]To introduce the surgical techniques and preliminary clinical results of electromagnetic navigation-guided percutaneous arch nails to fix thoracolumbar burst fractures. [Methods]From January 2020 to January 2022, 30 cases of single-stage thoracic and lumbar spine burst fractures were fixed by percutaneous peduncle nails under electromagnetic navigation guidance, and the patients were placed in the prone position during surgery, and the magnetic field generator, locator and navigation bridge were placed in turn, and after the C-arm fluoroscopic image was successfully matched with the electromagnetic navigation system, the percutaneous arch nails were fixed under the guidance of electromagnetic navigation. [Results]The number of C-arm machine fluoroscopy and the amount of bleeding of patients were significantly reduced during surgery. The functional evaluation indexes were evaluated by VAS score and ODI index, and the VAS score and ODI score of patients before surgery, 1 week after surgery, and the last follow-up were gradually reduced (P<0.05). The imaging evaluation indexes were evaluated by the Cobb angle and anterior edge compression ratio of the injured vertebra, and the Cobb angle and anterior edge compression rate of the injured vertebral were significantly reduced compared with the preoperative (P<0.05). [Conclusion]The application of electromagnetic navigation to guide percutaneous arch nails to fix thoracolumbar burst fractures can effectively restore the height of the injured vertebrae, significantly reduce the symptoms of patients, reduce the radiation exposure of doctors and patients, and restore spinal stability well.