Objective: To explore the clinical significance of the AI-assisted 3 D planning system (AIHIP) in THA, and to evaluate the accuracy and clinical value of the system in the clinical practical application. Methods: Among the 112 patients proposed to undergo THA from March 2020 to January 2022, 74 patients were preplanned using the AIHIP system (Intelligent group) and 38 patients using film templating measurement (Conventional group). The perioperative data, the matching degree between the intraoperative prosthesis and the preoperative planning prosthesis were compared, the postoperative Harris score, VAS score and hip flexion-extension activity (ROM) of the two groups were compared, and the postoperative imaging results of the two groups were analyzed and evaluated. Results: The prosthesis compliance rate was significantly higher than the conventional group, and the operation time was shorter than the conventional group (P <0.05). The Harris scores, VAS scores and ROM of the two groups were better than those before surgery. At 1 and 6 months after surgery, the Harris score, VAS score and ROM in the intelligent group were better than those in the conventional group, with a statistically significant difference (P <0.05). After surgery, the difference between longitudinal HCOR distance and transverse HCOR distance of intelligent group were smaller than that of conventional group, which was statistically significant (P <0.05). However, there was no significant difference between the LLD (P> 0.05) and the forward inclination and abduction angle of the acetabular components (P> 0.05). Conclusions: The preoperative planning assisted by AIHIP system has high accuracy, which can effectively help reconstruct the hip rotation center and shorten the operation time, and help the early recovery of hip function.