Abstract: [Objective] To explore the clinical efficacy of unilateral biportal endoscopic discectomy for double segment lumbar spinal stenosis. [Methods] A retrospective study was conducted on 8 patients who underwent unilateral biportal endoscopic discectomy for double segment lumbar spinal stenosis from October 2019 to October 2021. The visual analogue scale (VAS) for pain, Oswestry dysfunction index (ODI) and the modified Macnab criteria were used to evaluate the clinical efficacy. [Results] All the patients had operations completed successfully, with operative time of 192.5±14.14 min.Complications included dural sac tears in 1 case．All the patients were followed up for 6 － 15 months，with an average of (10.62±6.36) months.The Vas and Odi scores of patients with hip pain and lower limb radiating pain decreased significantly after Operation (P<0.05) . Over time, the symptoms became more pronounced.Based on Modified Macnab criterion, the clinical outcomes were marked as excellent in 5cases, good in 2 cases and fair in 1 case with excellent and good rate of 87.5%.[Conclusion] Unilateral biportal endoscopy is an effective method for treatment of double segment lumbar spinal stenosis