[Objective]To compare the effects of immediate post-operative weight-bearing activity and next-day weight-bearing activity on the recovery of patients undergoing hip and knee replacement under enhanced recovery after surgery.[Methods]A total of 140 patients who underwent primary total hip replacement (THA) and total knee replacement (TKA) in the department of Orthopaedics of our hospital from November 1, 2020 to May 31, 2021 were enrolled. The hospitalized patients were randomly divided into experimental group (66 cases) and control group (74 cases),Patients in the experimental group had weight-bearing activities immediately after surgery, while patients in the control group had weight-bearing activities on the first day after surgery.The weight bearing, first time of exhaust and defecation, complications and joint function scores were compared between the two groups.[Results]The gastrointestinal function of the experimental group recovered faster (first defecation time (h) 33.73±18.23 VS 45.57±22.87 P =0.02, the difference was statistically significant, and the joint function score of the experimental group was better than that of the control group, with statistical significance (P < 0.05),There was no significant difference in postoperative complications between the two groups (P < 0.05).[Conclusions] Immediate weight-bearing in patients with HTA/TKA can better promote the recovery of intestinal function and joint function without increasing complications.