疑似“集簇现象”1例病例报告
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1.濮阳市油田总医院;2.河南省濮阳市油田总医院

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国家科技攻关计划


A case report of suspected "cluster phenomenon"
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Puyang Oilfield General Hospital

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    摘要:

    “集簇现象”即8个月内出现至少5个节段的自发性胸椎和(或)腰椎骨折,临床十分罕见。本报道中患者系腺、垂体瘤术后,短时间内至少出现4次胸腰椎骨折,保守及PKP治疗后骨折症状均缓解,但患者最终死亡,可能死于腺垂体功能减退引起的激素危象。结论 当患者符合1.骨质疏松,尤其是激素水平异常或长时间使用糖皮质激素;2.短时间内二次骨折,尤其是可排除医源性因素后就应及时预判为“可疑集簇现象”,外科治疗的同时调整激素水平,警惕激素危象的发生。

    Abstract:

    The "cluster phenomenon" refers to the occurrence of spontaneous thoracic and/or lumbar fractures of at least 5 levels within 8 months, which is very rare in clinical practice. In this report, the patient had at least 4 thoracolumbar fractures in a short period of time after surgery for gland and pituitary tumors. The fracture symptoms were relieved after conservative and PKP treatment, but the patient eventually died, possibly due to hormonal crisis caused by adenopituitary dysfunction. . Conclusion When the patients meet 1. osteoporosis, especially abnormal hormone levels or prolonged use of glucocorticoids; 2. secondary fractures in a short period of time, especially after iatrogenic factors can be excluded, they should be promptly predicted as "suspicious group". "Cluster phenomenon", adjust hormone levels at the same time of surgical treatment, and be alert to the occurrence of hormonal crisis.

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  • 收稿日期:2022-05-13
  • 最后修改日期:2022-11-09
  • 录用日期:2022-11-15
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