富血小板血浆对髌骨骨折内固定的影响
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三峡大学第三临床医学院

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湖北省卫生计生委联合基金立项面上项目,宜昌市医疗卫生科研项目


Effect of platelet-rich plasma on internal fixation of patellar fractures
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The Third Clinical Medical College of China Three Gorges University

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Hubei Provincial Health and Family Planning Commission Joint Fund general project, Yichang Medical and health research project

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    摘要:

    摘要: [目的]研究富血小板血浆(PRP)对髌骨骨折内固定的影响。[方法] 选取髌骨骨折患者 50 例通过随机抽签法将其分为PRP组和无PRP组,每组 25 例。对照组无PRP组予以常规手术治疗,观察组PRP组分别比较两组术前一般资料,围手术期资料,随访资料及影像学资料。[结果] PRP组术后 3、6、12 月的 VAS 评分、 Bostman 评分和膝关节活动度均优于无PRP组(P<0.05)。PRP组手术时间、切口长度、术中失血量、下地行走时间、切口愈合、住院时间、早期VAS评分、完全负重活动时间、影像骨折愈合和髌股K-L分级与无PRP组无明显差异(P>0.05)。[结论] PRP 辅助治疗有利于促进髌骨骨折术后恢复,为膝关节功能恢复创造有利条件,减轻术后疼痛程度,改善膝关节功能结果,具有临床推广应用价值。

    Abstract:

    【Abstract】 [Objective] Investigate the effect of platelet-rich plasma (PRP) on internal fixation of patella fractures. [Methods] Fifty patients with patella fractures were selected and divided into PRP group and no PRP group by random drawing method, 25 patients in each group. The control group without PRP group was treated by routine surgery and the observation group PRP group was compared with two groups respectively for preoperative general data, perioperative data, follow-up data and imaging data. [results] The VAS scores, Bostman scores, and knee mobility of the PRP group at 3, 6, and 12 months after surgery were better than those of the group without PRP (P < 0.05). The operative time, incision length, intraoperative blood loss, time to ambulate, incision healing, hospital stay, early VAS score, time to full weight bearing activity, radiographic fracture healing, and patellofemoral K-L grade in the PRP group were not significantly different from those in the group without PRP (P > 0.05). [Conclusion] Adjuvant treatment with PRP is beneficial to promote postoperative recovery of patella fractures, create favorable conditions for knee functional recovery, reduce the degree of postoperative pain, and improve the functional outcome of the knee, which has clinical promoting application value。

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  • 收稿日期:2021-12-04
  • 最后修改日期:2022-03-15
  • 录用日期:2022-06-07
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