325例发育性髋发育不良患儿早期确诊影响因素分析
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空军军医大学

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陕西省自然科学基础研究项目 (2017JC2-04)


Analysis of influencing factors of early diagnosis of 325 children with developmental dysplasia of the hip
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Aire Force Medical University

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Natural science basic research project of Shaanxi Province(2017JC2-04)

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    摘要:

    [目的] 分析西北地区发育性髋关节发育不良(DDH)患儿早期确诊的影响因素,为DDH相关公共卫生政策的制定和推行提供科学依据。[方法] 回顾性纳入2011年1月至2020年12月西京医院收治的7岁以下DDH患儿325例作为研究对象,根据确诊时患儿年龄分为非延误组(确诊年龄0~6个月)和延误组(确诊年龄7~84个月)。调查内容包括:患儿的基本信息、家庭信息和诊疗信息。对不同确诊月龄与超声Graf分型和影像Crowe分型的关系进行Spearman相关性分析,而后根据分组进行单因素分析及多因素logistic回归分析。[结果] 共纳入325例患儿(432髋),其中非延误组72例、延误组263例。非延误组患儿确诊月龄与超声Graf分型存在弱负相关性(r=-0.284,p=0.016)。延误组患儿确诊月龄与影像Crowe分型存在弱正相关性(r=0.144,p=0.023)。多因素logistic回归结果表明家庭经济条件、母亲受教育程度、是否进行早期髋关节筛查是DDH患儿早期确诊的独立影响因素。[结论] 6个月以下确诊患儿确诊月龄与超声Graf分型呈弱负相关,7个月以上确诊患儿确诊月龄与影像Crowe分型呈弱正相关。家庭经济条件、母亲受教育程度、是否进行早期髋关节筛查是西北地区DDH患儿早期确诊的独立影响因素。

    Abstract:

    [Objective] To analyze the influencing factors of early diagnosis of children with developmental dysplasia of the hip (DDH) in northwest China, and to provide scientific basis for the formulation and implementation of DDH related public health policies. [Methods] A total of 325 children with DDH under 7 years old admitted to Xijing Hospital from January 2011 to December 2020 were retrospectively enrolled as the research subjects. According to the age of the children at diagnosis, they were divided into early diagnosed group (diagnosis age 0~6 months) and late diagnosed group (diagnosis age 7~84 months). The investigation included basic information, family information and diagnosis and treatment information of the children with illness. Spearman correlation analysis was carried out on the relationship between different diagnosis months and ultrasonic Graf classification and image crown classification, and then univariate analysis and multivariate logistic regression analysis were carried out according to the grouping. [Results] A total of 325 patients (432 hips) were included, including 72 cases in the early diagnosed group and 263 cases in the late diagnosed group. There was a weak negative correlation between the age of diagnosis and ultrasonic Graf classification in the early diagnosed group (r = -0.284, P = 0.016). There was a weak positive correlation between the age of diagnosis and Crowe classification in the late diagnosed group (r = 0.144, P = 0.023). The results of multivariate logistic regression showed that family economic condition, mother's education level and whether to carry out early hip screening were independent influencing factors for the early diagnosis of DDH children. [Conclusions] There was a weak negative correlation between the diagnosis age of patients under 6 months and ultrasonic Graf typing, and a weak positive correlation between the diagnosis age of patients over 7 months and imaging Crowe typing. Family economic condition, mother's education level and whether to carry out early hip screening were the independent influencing factors for early diagnosis of DDH in northwest China.

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  • 收稿日期:2021-10-19
  • 最后修改日期:2022-02-09
  • 录用日期:2022-05-11
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