Objective:In the study, human knee specimens were used for in vitro biomechanical study to compare the stability of suture hook suture and fast fix suture in repairing ramp injury of medial meniscus.Methods:Sixteen frozen human knee specimens were selected. The specimens were divided into four states: normal, modeling, ACL reconstruction and ACL reconstruction+Ramp injury repair. Ramp injury was repaired by suture hook suture (8 cases) and Fast-fix suture (8 cases). The tibial anteversion distance, internal rotation and external rotation angles of the knee were compared when the knee flexion was 0°, 30°, 60°and 90°under different states and suture techniques.Results:After ACL reconstruction, Fast-fix suture repair and suture hook suture repair, the tibial forward movement distance, internal rotation angle and external rotation angle at each flexion angle decreased (P＜0.05); There was no significant difference in tibial advancement between ACL reconstruction+Ramp repair (suture hook group) and ACL reconstruction+Ramp repair (Fast-fix group) (P＞0.005); The knee pronation of ACL reconstruction+Ramp repair (suture hook group) was less than that of ACL reconstruction+Ramp repair (Fast-fix group) at 0°, 30°and 60°flexion (P＜0.005). There was no significant difference between ACL reconstruction+Ramp repair (suture hook group) and ACL reconstruction+Ramp repair (Fast-fix group) at 90°flexion (P＞0.005); There was no significant difference between ACL reconstruction+Ramp repair (suture hook group) and ACL reconstruction+Ramp repair (Fast-fix group) at all knee flexion angles (P＞0.005).Conclusion:Under ACL reconstruction, suture hook suture and Fast-fix suture to repair the Ramp damage of medial meniscus can effectively improve the stability of knee joint, but compared with suture hook suture, Fast-fix suture can better restore the stability of tibial advancement and internal rotation of knee joint.