Abstract:Objective: Coronal tibiofemoral subluxation (CTFS) is a common imaging manifestation of knee osteoarthritis. However, due to the lack of standard measurement method and unclear mechanism, it has always been a difficult problem for joint surgeons. Methods: In PubMed, Embase, Cochrane Library, Web of Science and other international medical databases, the computer presented "Tibiofemoral", "Tibial and femoral", "instability", "Subluxation", "debris" and "CTFS" were used as keywords to conduct literature search, and relevant literatures were found and included in this study by manual selection according to inclusion criteria. Results: A total of 18 articles were included, of which 16 reported imaging measurement methods. Six were mechanisms and risk factors. Ten reported clinical outcomes. There is no unified standard for X-ray measurement of CTFS. At present, there are few studies on the mechanism of CTFS, and there are still controversies. The accepted theory is that the lateral ligament structure of the knee joint is more relaxed than the medial one. CTFS is a common radiographic manifestation of KOA, but is not of value in determining the severity of KOA. When it comes to clinical symptoms, research remains controversial. Conclusions: CTFS is not considered to be associated with KOA severity. However, attention should be paid to this problem in the stepwise treatment of knee joint to avoid complications due to poor ligament stability.