Abstract:Lung cancer is the main cause of cancer-related death worldwide with high mortality rate, and its poor prognosis is directly related to the characteristics of easy metastasis. Metastasis is an important sign of advanced lung cancer. The skeletal is common metastatic site of lung cancer. When imaging findings of bone metastasis from lung cancer is atypical, it is easy to escape diagnosis or be misdiagnosed. The atypical imaging findings of bone metastasis from lung cancer mainly include site and imaging findings. In this review, the patterns, imaging findings, diagnosis and imaging pitfalls of the atypical imaging findings of bone metastasis from lung cancer were summarized and the prospect of new technologies was made in order to improve our knowledge of the atypical imaging findings of bone metastasis from lung cancer and improve the prognosis.