MRI功能成像对强直性脊柱炎骶髂关节炎的疗效评价
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山东第一医科大学第二附属医院

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基于多模态影像技术对老年性骨质疏松的定量诊断价值,山东省2019年“学术提升计划”项目 (编号:2019QL017)


Effect evaluation of magnetic resonance functional imaging in ankylosing spondylitis
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The Second Affiliated Hospital of Shandong First Medical University

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Quantitative diagnostic value of multimodal imaging technology in senile osteoporosis,2019 "academic improvement plan" project in Shandong Province(

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    [目的]探讨MRI功能成像对早期AS骶髂关节炎的疗效价值。[方法]回顾48例AS患者,经中、西药综合治疗半年前、后均行骶髂关节MRI平扫及临床评价指标(BASDAI评分、CRP、ESR)。通过STIR获得SPARCC评分,通过IVIM获得定量参数(ADCslow、ADCfast、f)。比较治疗前、后MRI定量参数与临床AS疗效指标的变化及相关性。[结果] 临床疗效评价指标(BASDAI评分、ESR、CRP)与MRI定量参数(SPARCC评分、ADCslow、f)治疗后较治疗前降低(p<0.05)。SPARCC评分、ADCslow与BASDAI评分呈高度相关性(p<0.05)。[结论]MRI功能成像定量参数SPARCC评分和ADCslow、f能够有效的评估AS骶髂关节炎的治疗效果。

    Abstract:

    [Purpose] The study aimed to analyze efficacy evaluation for early AS sacroiliac arthritis using MRI functional imaging [Methods]Forty-eight patients with early active AS who were examined respectively by MRI and clinical therapeutic indexes(BASDAI score,CRP,ESR) before medication and after comprehensive treatment of Chinese and Western Medicine. SPARCC scores were obtained by STIR sequence, and the values of ADCslow, ADCfast, f were obtained by IVIM sequence before and after treatment .Comparison of the changes and correlation between MRI evaluation indexes and clinical indexes before and after treatment.[Results]The clinical evaluation indexes (BASDAI score, ESR, CRP) and MRI evaluation indexes (SPARCC score, ADCslow, f) after treatment were significantly lower than those before treatment (p<0.05). There were high correlation between SPARCC scores, ADCslow and BASDAI scores(p<0.05).[Conclusion] Quantitative parameters of MR Functional Imaging (SPARCC scores and the values of ADCslow, f )can effectively evaluate the therapeutic effect of AS sacroiliac arthritis.

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  • 收稿日期:2021-08-01
  • 最后修改日期:2021-10-14
  • 录用日期:2021-10-26
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