Abstract: [Objective] To analyze the preliminary clinical results of Socket-Anchor technique for ligament reconstruction in patients with lateral ankle instability. [Methods] Retrospective analysis was performed on 46 patients with lateral ankle instability admitted to the Department of Orthopedics in our hospital from February 2015 to March 2020. Among them, 24 cases were treated with Socket-Anchor ligament reconstruction, and 22 cases were treated with conventional incision for ligament repair and reconstruction. Preliminary clinical outcomes were compared between the two groups. [Results] The operation was successful in both groups, and no serious complications occurred. The operation time, total incision length, intraoperative blood loss and length of hospital stay in Socket-Anchor group were significantly better than those in incision group (P<0.05). The walking time and full loading activity time of Socket-Anchor group were significantly earlier than those of open group (P<0.05). At the last follow-up after surgery, ROM, AOFAS score and VAS score in 2 groups were significantly improved (P<0.05), and ROM, AOFAS score and VAS score in Socket-Anchor group were significantly better than those in incision group (P<0.05). In terms of imaging, the distance forward of the talus and the Angle of the talus inclination were significantly reduced in both groups at the last follow-up (P<0.001). However, at the same time point, there was no significant difference in the degree of talus forward displacement and the Angle of talus inclination between the two groups (P>0.05). [Conclusion] For lateral ankle instability, Socket-Anchor ligament reconstruction can achieve better clinical results than conventional open reconstruction surgery.