Abstract:Objective To explore the features and clinical effects of spinal canal anatomical reconstruction in intraspinal tumor resection. Methods From Feb. 2013 to May. 2017, tumor resection and anatomical reconstruction of spinal canal with center piece titanium plates were conducted for 48 patients. There were 28 males and 20 females. The age ranged from 21 to 56 years, with an average of 35.92±10.63 years old. The disease duration was 1-8 months with an average of 4.08±2.28 months. Tumors located in the thoracic, lumbar, and thoracolumbar region were 16, 20, and 12 cases, respectively. The ODI and Frankel classification were used to assess the quality of life and neurological function. Results Two patients had cerebrospinal fluid leakage after operation, which was cured after corresponding treatment. No other surgical complications were recorded. The 48 patients were followed up for 24-66 months with an average of 35.83±13.62 months. At final follow-up stage, the average ODI was 4.08±2.15, which was significant compared with preoperative ODI (t=6.442,P<0.05); Frankel grade was improved significantly when compared with preoperative grade (P<0.05); According to plain radiographs, The range of motion was increased significantly (t=8.375,P <0.05), no kyphosis, scoliosis, or instability was observed; CT showed the posterior spinal canal was well reconstructed; No tumor recurrence was observed. Conclusion Reconstruction of the spinal canal with center piece titanium plate in intraspinal tumors resection can maintain the volume of spinal canal, maintain the integrity of spinal bone-ligament structure, and protect the physiological functions of spine. It is a "functional surgery" and an effective procedure for the patients with intraspinal tumors.