Abstract: [Objective] to introduce the surgical technique and preliminary clinical results of induced membrane and tibial transfer in the treatment of talar osteomyelitis Methods] in a young patient with open comminuted fracture of talus caused by traffic injury, talus osteomyelitis was caused by infection after one-stage ankle fusion. The bone defect was filled by two-stage antibiotic bone cement induction membrane technology. After controlling the infection, the bone cement was taken out for tibial sliding and bone graft fusion from body iliac bone Results] the young patient was followed up for 8 months without secondary ulcer. The bone defect healing and adjacent joint function were evaluated by Paley method. The grade of fracture healing was excellent. Sanmantha X-line score 5 points. VAS score was 1 and AOFAS function score was 71 in August after operation Conclusion] the treatment of talar osteomyelitis with induced membrane and tibial transport is a feasible, safe and effective method, which can effectively control infection and improve postoperative walking function.