[Objective] To analyze the effect of axial displacement on wrist function after splint fixation of distal radius fractures. [Methods] From January 2019 to October 2019, 45 patients of distal radius axial displacement treated by manual reduction plus plintlet fixation. They were divided into two groups according to the degree of the radial axial displacement ＜2.5mm or ＞2.5mm at the last follow-up of 3 months after reduction. There were 24 cases in <2.5mm group, and 21 cases in >2.5mm group. The radial axial displacement, palm inclination angle and eulnar inclination angle was measured on X rays at the last follow-up, The functional results were scored with the Mayo scores system. The radial axial displacement, palm inclination angle, eulnar inclination angle and the Mayo scores were collected for statistical analysis between the two groups. [Results] At the last follow-up, it was found that the distal radius had different degrees of axial displacement. The average axial displacement was significant difference between the two groups (P<0.05); The average palmar inclination angle and the average ulnar deviation angle in the <2.5mm group were better than those in the <2.5mm group, with significant differences (P<0.05). there was no significant difference between the two groups in the average pain score (P>0.05), but the average function score, grip strength, range of motion and total Mayo score of the <2.5mm group were better than those of >2.5 mm, with significant differences (P<0.05). [Conclusion] Distal radius fracture treated by plintlet fixation have the phenomenon of axial displacement, the radial axial displacement <2.5mm may have less effect on the recovery of wrist function.