In recent years, the rapid development of 3D printing technology has become a new type of rapid prototyping and rapid manufacturing technology, which can quickly convert virtual X-ray films, CT and MR plane images of patients into three-dimensional objects, and can realize the personality of the material structure Customization and matching with the anatomy of the diseased parts have been widely used in the diagnosis, treatment and rehabilitation of orthopedic diseases, with broad application prospects. This article aims to review the cutting-edge research of 3D technology in orthopedics clinical and tissue engineering, summarize the existing problems, and look to the future.