两家医院1年内股骨粗隆间骨折老年患者死亡分析
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1.南京中医药大学常熟附属医院;2.苏州大学附属第三医院/常州市第一人民医院

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R683.42

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Death analysis of elderly patients with femoral intertrochanteric within one year after operation in two hospitals
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1.Changshu Hospital Affiliated to Nanjing University of Chinese Medicine;2.The Third Affiliated Hospital of Soochow University/Changzhou First People’s Hospital

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    摘要:

    [目的] 分析苏南地区两家医院老年股骨粗隆间骨折患者术后一年内死亡的危险因素。[方法] 回顾性分析苏南地区2家医院骨科2014年8月至2021年1月864例老年股骨粗隆间骨折患者的资料,分析年龄、性别、高血压、糖尿病、脑卒中、心脏疾病(包括心律失常、冠心病等)、肺部疾病(包括肺部感染、慢性阻塞性肺疾病(chronic obstructive pulmoriary disease, COPD)、哮喘等)、受伤至手术时间、住院时间、ASA评级、总蛋白、白蛋白、血红蛋白对患者生存预后的影响。[结果] 864例患者中术后一年内死亡144例,死亡率为16.7%。肺部感染为致死的最主要原因。通过Cox回归分析显示:年龄(HR=4.587, P<0.001)、白蛋白(HR=3.111, P=0.017)、肺部疾病(HR=2.341, P=0.042)、住院时间(HR=3.436, P<0.001)、美国麻醉协会分级(American society of anesthesiologists, ASA) (HR=3.377, P<0.001) 是导致老年股骨粗隆间骨折患者死亡的独立危险因素。绘制受试者工作特征曲线 (receiver operating characteristic curve, ROC)所得的预测死亡风险的年龄最佳临界点为83.5岁(敏感性69.4%, 特异性82.8%)。白蛋白水平最佳临界点为35.3g/L(敏感性88.9%,特异性48.9%)。住院时间最佳临界点为18.5天(敏感性72.2%,特异性90.0%)。[结论] 高龄、低白蛋白血症、肺部基础疾病、延长的住院时间、高ASA评分(III、IV分)是苏南地区65岁以上老年股骨粗隆间骨折术后一年内死亡的独立危险因素。

    Abstract:

    [Objective] To analyze risk factors for death within one year after operation in elderly patients with femoral intertrochanteric fractures in two hospitals in southern Jiangsu. [Methods] A total of 864 femoral intertrochanteric fracture patients from August 2014 to January 2021 were retrospectively analyzed in two hospitals. The age, gender, hypertension, diabetes, stroke, cardiac diseases (including arrhythmia, coronary heart disease, etc.), pulmonary diseases (including pulmonary infection, COPD, asthma, etc.), time from injury to operation, length of stay, ASA grading, hemoglobin, albumin and total protein were analyzed to find risk factors for one year mortality after femoral intertrochanteric fracture surgery. [Results] Among the 864 patients, 144 died within one year after operation, and the mortality was 16.7%. The main cause of death was pulmonary infection. Cox regression analysis showed that age (HR = 4.587, P < 0.001), albumin (HR = 3.111, P = 0.017), lung disease (HR = 2.341, P = 0.042), length of hospital stay (HR = 3.436, P < 0.001) and ASA rating (HR = 3.377, P < 0.001) were the independent risk factors for one year mortality after femoral intertrochanteric fracture surgery in elderly patients. The best cut-off point of age for predicting the risk of death from the receiver operating characteristic (ROC) curve was 83.5 years (sensitivity 69.4%, specificity 82.8%). The best cut-off points of albumin level and hospital stay were 35.3g/L (sensitivity 88.9%, specificity 48.9%) and 18.5 days (sensitivity 72.2%, specificity 90.0%) by ROC curve analysis, respectively. [Conclusion] Old age, hypoalbuminemia, underlying lung diseases, prolonged hospital stay, and high ASA score (III, IV) are independent risk factors for death within one year after surgery for intertrochanteric fractures in the elderly over 65 years old in southern Jiangsu.

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  • 收稿日期:2021-02-26
  • 最后修改日期:2021-05-18
  • 录用日期:2021-06-22
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