Objective: To explore the clinical effect and safety of Ponte osteotomy in the correction of thoracolumbar kyphosis. Methods: The clinical data of 35 cases of thoracolumbar kyphosis treated with Ponte osteotomy from January 2006 to December 2017 were analyzed. There were 9 males and 26 females; they were 27-72 years old, with an average of (62.67±10.7) years old. All showed chronic low back pain, combined with 5 cases of spinal cord tension injury. Routinely performed X-rays of the full length of the spine and lateral flexion and extension of the thoracolumbar spine, CT scan and reconstruction of the thoracolumbar spine, and MRI examination of the thoracolumbar spine. Causes of kyphosis: 11 cases of degenerative lesions, 22 cases of old fractures, and 2 cases of ankylosing spondylitis. 17 cases were combined with 1 item of underlying disease, and 8 cases were combined with 2 items. Bone density value: 1.3～-3.32SD, average (-1.97±0.56) SD. All were performed Ponte osteotomy, including 22 cases of 3-segment osteotomy, 9 cases of 4-segment osteotomy, 2 cases of 5-segment osteotomy, 1 case of 10-segment osteotomy, two-segment Ponte osteotomy + single vertebral body In 1 case of PSO osteotomy, 124-segment Ponte osteotomy and 1 single-vertebral PSO were performed. Record the general situation of the operation, observe and compare the VAS score of low back pain, ODI dysfunction index, and the changes of imaging indicators before and after the operation and at the final follow-up. Results: The average operation time was (197±52.54) minutes, the average intraoperative blood loss was (747.62±414.75) ml, and the postoperative drainage fluid volume was (262.36±53.68) ml. In this group of cases, except for 1 case of poor incision healing, the rest healed by first intention. Postoperative imaging examinations revealed that 1 case of mouth opening occurred in the intervertebral space in front of the osteotomy segment, 1 case of postoperative cerebral barren fluid leakage, and 1 case of spinal nerve injury. Spinal nerve injury was classified as C grade according to the ASIA classification. The cause of the injury was considered to be local compression of the osteotomy segment. After timely decompression of the spinal canal, the spinal nerve symptoms and signs were completely recovered three months after the operation. The follow-up time was 6 to 60 months, with an average of (34.2±11.55) months. During the follow-up, 2 cases of the distal screw were slightly pulled out, and the rest had no internal fixation loosening or breakage, and no obvious degeneration of adjacent segments or junctional kyphosis. Through the comparison of imaging indexes before operation, after operation and at the final follow-up, the parameters of the spine and pelvis in this group of patients were recovered well, and they were well maintained at the final follow-up. Spine sagittal deformity (Cobb angle) recovered from the preoperative average (34.33±14.58)° to the postoperative average (11.93±6.26)°, with an average correction of 22.75° for each case, and an average correction of 6.28° for each Ponte osteotomy. At the final follow-up, the patient’s low back pain was significantly relieved. The VAS score decreased from the preoperative average (6.7±0.78) to the final follow-up average (1.2±0.35). The ODI dysfunction index decreased from the preoperative average (62.3%). ±8.10)% recovered to the average (19.31±7.22)% at the last follow-up. Regardless of the VAS score or ODI dysfunction index, there were statistical differences between the final follow-up and the preoperative comparison. There were 3 complications in this group, with an incidence rate of 8.57%. Conclusion: As long as the surgical indications and case selection are strictly controlled, Ponte osteotomy is a simple, safe and effective orthopedic method, with good clinical application value, and can be a good choice for the correction of thoracolumbar dorsal kyphosis.