Objective: To investigate the clinical effect of combined external fixation and plate fixation after cubitus varus orthopedic osteotomy. Methods: A total of 75 patients with cubitus varus treated in our hospital from January 2013 to December 2019 were analyzed retrospectively. According to the different fixation methods after cubitus varus orthopedic osteotomy, the patients were divided into external fixation group (n=47) and internal fixation group (n=28).The operation time, intraoperative blood loss, incision length and postoperative complications of the two groups were observed and recorded. The function of elbow joint was evaluated according to Bellemore standard in the last follow-up. Results: Both groups achieved satisfactory function and appearance after operation, and there were no complications such as incision infection, nerve injury, bone nonunion, and fixation failure.The operation time, intraoperative blood loss, and surgical incision length of the external fixation group were less than those of the internal fixation group, which was statistically significant( P<0.001).At the last follow-up, the range of elbow joint range of motion, lifting angle and anteversion angle were not statistically significant(p>0.05).The postoperative elbow joint function was evaluated according to Bellemore's standard, and there was no statistical difference (p>0.05). Conclusion: The cubitus varus orthopedic osteotomy is fixed with combined external fixator , which has the advantages of shorter operation time, smaller incision, more convenient operation, less postoperative residual scar and earlier functional exercise.