[Abstract] Objective To introduce the surgical technique and preliminary results of oblique lateral interbody fusion in the treatment of lumbar tuberculosis. Methods From October 2018 to June 2020, 13 patients with lumbar tuberculosis were admitted to the Department of Orthopaedics of our hospital. The latest treatment was oblique lateral interbody fusion: taking the lateral position, entering the extraperitoneal space through the oblique muscles outside the abdomen, the oblique muscles inside the abdomen and the transverse muscles of the abdomen, reaching the lateral side of the lumbar spine, removing the lesions, taking the iliac bone graft, and finally fixing the vertebral body with screws. Results The average operation time was (132.51±21.40)min and the blood loss was (227.32±43.14)ml. Seven days after operation, ESR, CRP and VAS scores were better than those before operation. After operation, the neurological function of patients improved without obvious complications. Conclusion Oblique lateral interbody fusion is a new minimally invasive surgery for lumbar tuberculosis, which has the advantages of less trauma, short operation time, less bleeding, thorough lesion clearance, safety and effectiveness, and has a good early clinical effect for lumbar tuberculosis.