【Abstract】Objective: To investigate the clinical application value of 3D printed template guided hollow screw placement for fixation femoral neck fracture. Methods： Clinical data of 40 patients with femoral neck fracture treated with hollow screws fixation in putuo hospital from June 2018 to December 2019, were randomly divided into 3D printed template guide drilling group (3D template group) and traditional locator guide drilling group (conventional group) 20 cases. Analyze the statistics of surgical wound length、operation time、drilling attempts、amount of intraoperative bleeding、follow-up Harris and VAS score、range of motion、screw parallelism and screw dispersion. Results: There was no significant differences in surgical wound length between the two groups(P>0.05).In the 3D template group ,the operation time 、 drilling attempts and amount of intraoperative bleeding were less than those in the conventional group, Significant differences were found concerning all above parameters between the two groups(P<0.05);There was no significant differences in Harris and VAS score 、range of motion before surgery、1 week after surgery and at the last follow up between the two groups(P>0.05).In addition, Harris and VAS score 、range of motion of the two groups were significantly improved 1 week after surgery and at the last follow up, the differences were statistically significant. In the 3D template group: screw parallelism and screw dispersion were better than those in the conventional group, Significant differences were found concerning all above parameters between the two groups(P<0.05) , Conclusion: 3D printed template guided hollow screw placement for fixation femoral neck fractures can reduce the number of drilling attempts、short the operation time、reduce amount of intraoperative bleeding and improve the screw parallelism and screw dispersion of screws. So 3D printed template guided hollow screw placement for fixation femoral neck fractures can achieve a good therapeutic effect.