DTI技术参数预测脊髓型颈椎病术后运动功能恢复的价值分析
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河北北方学院附属第二医院

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张家口市重点研发计划项目(名称:神经阻滞联合热敏灸治疗腰间盘突出MRI影像改变研究,编号:1921018D)


Value analysis of DTI technical parameters in predicting motor function recovery after cervical spondylotic myelopathy
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The Second Affiliated Hospital of Hebei North University

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    摘要:

    目的:探讨DTI技术参数预测脊髓型颈椎病(CSM)术后运动功能恢复的价值。方法:选取32例手术治疗的CSM患者以及32例正常者,分别于术前与术后行常规磁共振成像(MRI)以及弥散张量成像(DTI)检查;比较两组术前与术后中央前回(PrCG)、中央后回(PoCG)的激活体积(VOA)值以及脊髓的各向异性分数(FA)值;统计分析各DTI指标与日本骨科学会评分系统(JOA)评分、评分好转率间的相关性;分析DTI指标预测CSM术后恢复不良的ROC曲线以及CSM患者术后恢复不良的因素。结果:(1)CSM患者术后JOA评分显著大于术前(P<0.05),术前CSM组PrCG显著大于对照组,FA显著小于对照组(P<0.05);CSM组术后与术前比较,PrCG显著减小,FA显著增大(P<0.05);(2)DTI各项指标与术前JOA评分、术后评分好转率之间均具有显著相关性(P<0.05),VOA比值与术后评分好转率相关系数最大;(3)所有CSM患者术后随访中按JOA评分好转率分为良好组与不良组,2组患者横截面积(CSA)、FA、PrCG以及VOA比值之间比较差异具有统计学意义(P<0.05);且VOA比值的AUC面积最大;(4)VOA比值以及FA值是预测CSM术后恢复不良的危险因素。结论:DTI技术中VOA比值以及FA值是预测CSM患者术后运动功能恢复的危险因素。

    Abstract:

    Objective: To explore the value of DTI technical parameters in predicting postoperative motor function recovery of cervical spondylotic myelopathy (CSM). Methods: 32 patients with CSM and 32 normal patients who underwent surgical treatment were selected for routine magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) before and after surgery; the preoperative and postoperative centers were compared between the two groups Anterior gyrus (PrCG), central posterior gyrus (PoCG) activation volume (VOA) values and spinal cord anisotropy score (FA) values; statistical analysis of various DTI indicators and the Japanese Orthopedic Association scoring system (JOA) score Correlation; analysis of the ROC curve of DTI indicators predicting poor recovery after CSM and factors of poor recovery after CSM. Results: (1) Postoperative JOA score of CSM patients was significantly greater than preoperative (P<0.05), PrCG of preoperative CSM group was significantly greater than that of control group, FA was significantly smaller than control group (P<0.05); CSM group compared postoperatively with preoperative , PrCG decreased significantly, FA increased significantly (P<0.05); (2) There was a significant correlation between the DTI indicators and the preoperative JOA score, postoperative score improvement rate (P<0.05), VOA ratio and The correlation coefficient of postoperative score improvement rate is the largest; (3) All CSM patients are divided into good group and bad group according to JOA score improvement rate during the postoperative follow-up. The cross-sectional area (CSA), FA, PrCG and VOA ratios of the 2 groups of patients The difference was statistically significant (P<0.05); the AUC area of VOA ratio was the largest; (4) VOA ratio and FA value were the risk factors for predicting poor recovery after CSM. Conclusion: The VOA ratio and FA value in DTI technology are the risk factors for predicting postoperative motor function recovery in CSM patients.

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  • 收稿日期:2020-07-07
  • 最后修改日期:2020-10-09
  • 录用日期:2020-10-16
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