Silk fibroin (SF), as a natural bioremediation material, can be processed into hydrogels, electrospun nanofibers, sponge-like porous scaffolds, and 3D printed scaffolds to repair bone tissue. It has good biocompatibility It has the advantages of non-toxicity, non-toxic degradation products and adjustable mechanical properties. Research in recent years has shown that through the implantation of various cells, different chemical modifications, and loading of various growth factors, the application of silk fibroin bioscaffolds in bone tissue engineering has become more and more extensive, especially the emerging 3D printing The SF scaffold can largely solve the problems encountered in bone tissue engineering, and will bring better quality of life for more patients with bone diseases in the future. This article reviews the latest application progress of silk fibroin biomaterials in bone tissue engineering in recent years.