[Objective] To introduce the technical points and clinical efficacy of anterior intervertebral osteotomy and fusion ( AIOF) for severe cervical spondylosis. [Methods] 37 patients with severe cervical spondylosis received anterior intervertebral osteotomy and fusion ( AIOF)from May 2015 to June 2017. There were 25 patients were male and 12 were female，aged 25～52 years. There were 11 cases in single segment，15 cases in double segment，8 cases in 3 segments and 3 cases in 4 segments．Visual Analogue Score ( VAS) and Japanese Orthopaedic AssociationScore ( JOA) were used to evaluate the clinical efficacy．[Results] The operation time was 112 minutes( 65～190 minutes) and the intraoperative blood loss was 61 ml ( 35～180 ml) . All 37 patients successfully completed the operation without complications such as cerebrospinal fluid leakage , nerve root injury, vertebral artery injury and C5 nerve root palsy. All 37 patients were followed up 13～26 months, with an average of （15.32±2.55）months. Japanese Orthopaedic Association Score ( JOA) increased from 9.40±0.50 before the surgery to 14.84±0.37 at the last follow-up, had significant difference(t＝-53.091，P＜0.05). The visual analogue scale (VAS) decreased from 6.13±0.82 before the surgery to 0.89±0.61 at the last follow-up, had significant difference(t＝31.087，P＜0.05). CT showed good intervertebral bone fusion. [Conclusion] Anterior intervertebral osteotomy and fusion ( AIOF) for severe cervical spondylosis is safe and feasible, with sufficient decompression and satisfactory clinical efficacygood clinical effect. It is especially suitable for patients with cervical spondylosis with intervertebral stenosis and severe osteophyte hyperplasia behind the vertebral body.