新鲜同种异体软骨修复髋关节软骨缺损
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天津市第一中心医院

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Fresh Osteochondral Allograft repair hip cartilage defect
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Tianjin Frist Central Hospital

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    摘要:

    介绍新鲜同种异体软骨移植修复髋关节软骨缺损的手术技术与初步结果。 方法 2019年3月-2019年5月,采用新鲜同种异体软骨移植技术修复3例髋关节软骨损伤患者,平均年龄39.6岁。外科脱位技术暴露髋关节,清除损伤软骨及软骨下骨组织,将新鲜同种异体骨软骨制备成适合大小固定于缺损处。术后卧床12周、4周、3个月、6个月进行双髋正位片,髋关节CT检查,进行Harris评分、SF-12评分、VAS评分。结果 术后平均随访10.6±1.15个月。Harris评分、SF-12功能评分、心理评分、VAS评分,术前35.00±7.00、25.07±2.37、23.82±9.82、8.33±0.58 VS术后76.67±10.07、37.51±5.94、61.35±5.17、1.67±1.53。术后CT显示移植物与宿主骨均融合,移植物无囊性变及脱落。结论 新鲜同种异体软骨移植术后关节功能明显改善,可作为治疗大面积软骨缺损的方法,远期疗效还需要大宗病例报道及随访结果证实。

    Abstract:

    Objective To introduce the surgical technique and preliminary results of fresh Osteochondral Allograft to repair hip cartilage injury. Methods From March 2019 to May 2019, three patients with hip articular cartilage defect were repaired by fresh Osteochondral Allograft technology, average age of 39。6 years. Surgical hip dislocation technique exposes the hip joint, removes the damaged cartilage and subchondral bone, prepares fresh allograft to fit the size of the defect. After surgery, stay in bed for 8~12 weeks. Direct radiographs of both hip and hip CT examinations, 4 weeks, 3 months, and 6 months after surgery, and assessment of Harris score, SF-12 score, VAS score. Results The average follow-up time was 10.6±1.15 months, The postoperative Harris score, SF-12 physical score, mental score, and VAS score were : pro-operation 35.00±7.00、25.07±2.37、23.82±9.82、8.33±0.58 vs post-operation 76.67±10.07、37.51±5.94、61.35±5.17、1.67±1.53 respectively. Postoperative CT showed that the graft and the host bone were fused, and the graft had no cystic changes and fell off. Conclusion After fresh Osteochondral Allograft operation, the joint function is significantly improved, which can be used as a method for the treatment of large-scale cartilage defect. Long-term efficacy also needs to be confirmed by a large number of case reports and follow-up results.

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  • 收稿日期:2020-04-07
  • 最后修改日期:2020-08-12
  • 录用日期:2020-08-21
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