[Objective] The study was aimed to analyze the clinical efficacy of bridge combined internal fixation systems and locking plates on unstable pelvic fractures, then provide a basis for the choice of treatment options for patients. [Methods] In total, 68 unstable pelvic fractures patients in Taian Central Hospital in the past 5 years were enrolled in the study. Then, 34 cases were divided in the bridge combined internal fixation group and 34 cases were in the locking plate internal fixation group. The length of the surgical incision, the amount of intraoperative blood loss, and the operation time of the two groups were recorded. X-ray examination was performed regularly after suergery, and the situation of fracture reduction and fixation were evaluated according to Matta criteria. Statistical analysis was performed using SPSS19.0 statistical software. [Results] Compared with the locking plate fixation group, patients underwent combined internal fixation required less operative time (103.5 ± 61.087 min vs. 166.8 ± 63.992 min, P < 0.01), less intraoperative bleeding (272.4 ± 102.414mL vs. 444.1 ± 214.834mL, P < 0.01), shorter length of surgical incision (17.1 ± 3.771cm vs. 22.8 ± 3.766 cm, P < 0.01), shorter fracture healing time (9.4 ±1.574 weeks vs. 11.1±1.893 weeks, P < 0.01). There was no significant difference in limb function recovery between the two groups (P > 0.05). According to the Matta fracture reduction criteria, all patients in both groups were excellent. [Conclusion] The data from this study show that the bridged internal fixation system has more advantageous for the treatment of patients with unstable pelvic fractures. However, the long-term surgical efficacy and data representation of this system are still needed in further research due to its short clinical application time.