Abstract:［Objective］To compare the clinical efficacy of anterior skip corpectomy and fusion (SCF) and posterior single open-door laminoplasty (LP) in the treatment of long-level cervical spondylotic myelopathy.［Methods］Retrospective analysis of 42 patients with long-level cervical spondylotic myelopathy who underwent surgery in our hospital from March 2012 to October 2015, including SCF group 19 cases and LP group 23 cases. The operative time, intraoperative blood loss and hospital stay of the two groups were recorded. The JOA score, VAS score, NDI score and postoperative complications were used to evaluate the therapeutic effect.［Results］The length of stay of the SCF group was shorter than that of the LP group, and the difference was statistically significant (P<0.05). Comparison within the two groups, the JOA score, VAS score, and NDI score after surgery were significantly improved compared with those before surgery. The cervical lordosis of patients in the SCF group increased after surgery compared with that before surgery, and the difference was statistically significant (P<0.05). The cervical lordosis of patients in the LP group decreased at the last follow-up compared with that before surgery, and the difference was statistically significant (P<0.05). Between the SCF group and the LP group, the differences in cervical lordosis were statistically significant (P<0.05). The SCF group had more complications than the LP group, and the difference was statistically significant (P<0.05).［Conclusion］Both of the two surgical procedures can effectively treat long-segment cervical spondylotic myelopathy. The SCF surgery has advantages in the reconstruction and maintenance of cervical lordosis, and the complications of LP surgery are relatively rare.