[Objective] To analyze the efficacy of dual mobility total hip arthroplasty in the treatment of hemiplegic limb femoral neck fracture in post-stroke patients. [Method] A retrospective analysis was made on 21 patients with hemiplegic limb femoral neck fracture treated in the Department of Orthopaedics, Aerospace Center Hospital from January 2017 to June 2019. All patients were treated with dual mobility total hip arthroplasty. The therapeutic effect was evaluated from the aspects of visual Analogue Score (VAS), Harris score and imaging data. [Results] All patients survived the perioperative period safely, and the incision healed well after operation. there were no complications such as infection, vascular/nerve injury, rejection, prosthesis loosening, joint dislocation and periprosthetic fracture. the average follow-up time was 11.7 months (7 to 19 months). The mean value of VAS was 6.1 ±1.7 before operation and 2.4 ±0.9 one week after operation, the difference was statistically significant (P＜0.05). The average Harris score was 33.5 ±3.8before operation, and there was a linear relationship between the follow-up nodes and the follow-up time. The final follow-up was 84.7 ±6.2points, including excellent in 5 cases, good in 11 cases, fair in 2 cases and poor in 3 cases. the excellent and good rate of treatment was 76.2% (16/21). the difference was statistically significant (P＜0.05). [Conclusion] Dual mobility total hip arthroplasty for the treatment of hemiplegic limb femoral neck fracture in post-stroke patients can avoid the occurrence of postoperative prosthesis dislocation, and can be used selectively for patients whose muscle strength of the affected limb is less than grade Ⅲ, combined with active postoperative rehabilitation training. a good therapeutic effect can be obtained.