中国人同期与分期双侧全髋关节置换术后疗效的meta分析
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南昌大学第三附属医院

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江西省卫生计生委科技计划


Meta analysis on efficacy of simultaneous versus staged bilateral total hip arthroplasty in Chinese patients
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The third affiliated Hospital of Nanchang University

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Scientific research project of Jiangxi provincial health commission.

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    摘要:

    [目的]:采用meta分析的方法,比较中国人群中同期与分期双髋置换术的疗效。[方法]:检索PubMed、Embase、Cochrane library、Web of science、中国知网、万方等数据库中关于双侧全髋置换同期与分期治疗的研究,检索年限为建库至2020年1月,依据纳入及排除标准筛选文献,提取数据,采用Review Manager 5.2软件分析。[结果]共纳入文献12篇,病例数共989例(同期组539例,分期组450例)。Meta分析显示,同期组在手术时间、住院时间、出血量、住院费用优于分期组,而同期组增加输血量(p<0.05)。两组在术后Harris评分、深静脉血栓、肺栓塞、术后感染率及术后神经精神系统症状发生率的差异均无明显统计学意义(p>0.05)。[结论]本次研究表明,同期组能缩短手术时间及住院时间,降低出血量和住院费用等指标优于分期手术,同期组输血量高。

    Abstract:

    [objective]To compare efficacy of simultaneous versus staged bilateral total hip arthroplasty in Chinese patients.[Method]The database of PubMed,Embase,Cochrane library,Web of science ,CNKI and Wanfang Database were searched online.All the trials comparing simultaneous versus staged bilateral total hip arthroplasty were included under the inclusion and exclusion criteria and the related data were extracted before January 2020,the Review Manager 5.2 were used for data analysis.[Results]12 studies met the inclusion criteria,which included a total of 989 cases(539 simultaneous bilateral THA,450 staged bilateral THA).The results of meta-analysis showed that the operation time,hospital stay,and blood loss volume,hospitalization expenses were significantly better in simultaneous bilateral THA group than in staged bilateral THA group.The blood transfusion volume were significantly higher in simultaneous group(p<0.05).In addition,there was no significantly difference in the postoperative Harris scores,risk of deep vein thrombosis,pulmonary embolism,wound infection and neuropsychiatric symptoms. [Conclusion]The current research evidence shows that the operation time,hospital stay,blood loss volume and hospitalization expenses were significantly better in the simultaneous bilateral THA group.but the blood transfusion volume were significantly higher in simultaneous group.

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  • 收稿日期:2020-01-12
  • 最后修改日期:2020-03-14
  • 录用日期:2020-04-01
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