【Abstract】Objective The purpose of this study is to report the imaging characteristics of one case of Nora’s lesion of the left femur lateral, and review relevant literatures in order to improve the recognition level and dignosis level of Nora’s lesion.Methods To analyze the characteristics and imaging manifestations of a 41-year-old man with Nora’s lesion in our hospital.A total of 82 cases patients with Nora''s lesion reported from October 1, 2009 to October 1, 2019 by using "Nora’s lesion" or "bizarre parosteal osteochondromatous proliferation" as keywords to search in PubMed、cnki 、Weipu and wanfang databases. Combined with the imaging features of this case,to analyze the clinical and imaging characteristics of Nora’s lesion.Results The age of 83 cases during 0-79 years old, and the average age is 32.6±17 years old.There are 46 male patients，36 female patients and 1baby unknow gender.The ratio is about 1.3:1.There were 54 cases involves the small tubular bones of the hands and feet,and other locations also involved. Pathological examination indicated that bone, cartilage and fibrous tissue were observed in the submitted tissues (left thigh), which were interspersied and grown in skeletal muscle. Osteoblasts and osteoclast giant cells were observed around the bone tissues, and the cartilage tissues were heterogenous. Finally,Benign lesions are considered, with a tendency toward bizarre parosteal osteochondromatous proliferation. According to the literature,Nora’s lesion performed as a heterogeneous high density shadow in X - ray or CT.On MRI, the lesion is usually hypo- to isointense on T1-weighted sequences and iso-to hyperintense on T2-weighted sequences and fat suppression sequences,which demonstrate enhancement following contrast administration. Conclusion Nora’s lesion is a rare benign exophytic proliferative lesion that predominantly involves the small tubular bones of the hands and feet,the most performance are local mass. The imaging findings characterized by a radiodense mass adjacent to the bone surface.On MRI, the lesion is usually hypo- to isointense on T1-weighted sequences and iso-to hyperintense on T2-weighted sequences and fat suppression sequences,which demonstrate heterogeneous enhancement following contrast administration. Pathological examination revealed "blue bone".Surgical resection is the main treatment, and postoperative recurrence rate is higher. Nora’s lesion usually has no malignant change tendency.