Mini-cog量表可以简单有效地筛选老年髋部骨折术后谵妄发生的高危患者
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北京大学第一医院

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Mini-cog as a simple and effective way to screen high risk of delirium among elderly patients after hip fracture surgery
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Peking University 1st Hospital

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    摘要:

    [目的]研究老年髋部骨折患者术后谵妄状态的发生率及相关危险因素。探究Mini-cog量表评分与谵妄发生的关系。[方法]70例接受手术治疗的老年髋部骨折患者,收集患者术前血清钠离子浓度、术前牵引制动、术前卧床天数、手术时间、术后3天血色素下降值、吗啡类药物使用、术后入外科监护室、术后7日内是否出现谵妄等信息,计算患者Charlson共病指数,进行MMSE量表和Mini-cog量表评分并记录所用时间。[结果]术后7日内有28例(40%)患者出现谵妄状态。谵妄组患者较非谵妄组术前卧床时间长(P<0.01),术前血清钠离子浓度值低(P=0.011),术后3天血色素下降多(P<0.01),术前Charlson共病指数高(P=0.007)。评估术前认知状态的MMSE和Mini-cog量表评分谵妄组显著低于非谵妄组(P=0.044, 0.028)。术后谵妄与术前卧床时间(OR=2.139,95%CI 1.372-3.333)、术前血清钠离子浓度(OR=0.831,95%CI 0.722-0.956)、术前Charlson共病指数(OR=1.598,95%CI 1.118-2.284)、术前MMSE量表评分(OR=0.949,95%CI 0.905-0.996)和Mini-cog量表评分(OR=0.685,95%CI 0.498-0.942)均相关。完成Mini-Cog量表时间(3.9±1.6分钟)显著低于MMSE量表(12.1±4.8分钟)(P<0.001)。[结论]老年髋部骨折患者术后谵妄状态的发生与术前卧床时间、术前血清钠离子浓度、术前Charlson共病指数、术前MMSE量表评分和Mini-cog量表评分相关。评估认知功能障碍的Mini-cog量表可以简单有效地筛选老年髋部骨折术后谵妄发生的高危患者。

    Abstract:

    [Objective] To investigate the incidence of postoperative delirium and its related clinical risk factors in elderly patients with hip fracture. To explore the relationship between Mini-cog scale score and delirium. [Methods] 70 elderly patients with hip fracture underwent surgery in our hospital were included. We collected patients’preoperative serum sodium concentration, preoperative traction, preoperative non-ambulatory days, length of operation, decline in hemoglobin on the third day after surgery, morphine drug use, admitting in the intensive care unit, Charlson comorbidity index, and onset of delirium within 7 days after surgery. Each patient was administered the MMSE and Mini-cog by the primary nurse, and the duration time were documented. [Results] Twenty-eight patients (40%) developed delirium within 7 days after surgery. Preoperative non-ambulatory time was longer in delirium group than in non-delirium group (P<0.01), preoperative serum sodium concentration was lower (P=0.011), decline in hemoglobin on the third day after surgery was higher (P<0.01), and Charlson comorbidity index was higher (P=0.007). MMSE and Mini-cog scores were significantly lower in delirium group than the non-delirium group (P=0.044, 0.028). The results of single factor logistic analysis showed that the risk factors for postoperative delirium were preoperative non-ambulatory time (OR=2.139,95%CI 1.372-3.333,P=0.001), preoperative serum sodium concentration (OR=0.831,95%CI 0.722-0.956,P=0.010), Charlson comorbidity index (OR=1.598,95%CI 1.118-2.284,P=0.010), MMSE score (OR=0.949,95%CI 0.905-0.996,P=0.035) and Mini-cog score (OR=0.685,95%CI 0.498-0.942,P=0.020). To finish the Mini-Cog cost 3.9±1.6 minutes, which was significantly less than MMSE(12.1±4.8 minutes) (P<0.001). [Conclusion] The onset of postoperative delirium of elderly patients after hip fracture surgery is associated with preoperative non-ambulatory time, preoperative serum sodium concentration, Charlson comorbidity index, preoperative MMSE and Mini-cog scores. Mini-cog as a simple and effective way to assess cognitive impairment could screen high risk of delirium among elderly patients after hip fracture surgery.

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  • 收稿日期:2019-10-15
  • 最后修改日期:2019-10-15
  • 录用日期:2019-12-20
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