Abstract Objective: Microscopy-assisted minimally invasive posterior laminoforaminotomy for the treating cervical spondylotic radiculopathy caused by laterally protruding cervical disc or spur. This paper mainly discusses this methods and efficacy of cervical spondylotic radiculopathy. Methods: From November 2016 to March 2019, 30 patients diagnosed with cervical spondylotic radiculopathy with unilateral root symptoms were diagnosed by radiographic examinations such as X-ray, CT, and MRI. Microscopically assisted minimally invasive posterior posterior laminoforaminotomy was performed in these patients. Clinical outcomes were evaluated by VAS scores of unilateral upper extremity pain and modified Odom''s criteria before and after surgery, and magnetic resonance was used to judge the effect of postoperative decompression. Results: According to the modified Odom''s criteria, the excellent and good rate of microsurgical minimally invasive posterior lumbar intervertebral foramen enlargement was 46.7%, and the improvement rate was 86.7%. Most patients had significant relief of unilateral upper extremity radiation pain after surgery, and no significant complications occurred during the entire follow-up period. Conclusion: The use of microscopy to assist the minimally invasive posterior laminoforaminotomy has a significant clinical effect in the treatment of cervical spondylotic radiculopathy, and has a certain promote significance.