颈椎前路椎间盘切除融合术后邻近节段退变与矢状位参数的相关性研究
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1.广西中医药大学第一附属医院;2.广西中医药大学

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国家自然科学基金项目(面上项目,重点项目,重大项目)


Correlation between adjacent segment degeneration and sagittal parameters after anterior cervical discectomy and fusion
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1.The First Affiliated Hospital of Guangxi University of Chinese Medicine;2.Guangxi University of Chinese Medicine

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    摘要:

    摘 要:[目的] 探讨颈椎前路椎间盘切除融合术后邻近节段退变与颈椎矢状位参数的相关性。[方法] 回顾分析2012年1月至2017年12月在广西中医药大学第一附属医院脊柱外科因脊髓型颈椎病接受颈椎前路单节段椎间盘切除融合术(ACDF)手术且随访资料完整的76例患者资料,并依据随访期间是否出现邻近节段退变分为退变组和无退变组。记录两组患者的一般资料(性别、年龄、体质量指数等)以及颈椎矢状位参数(C2-7Cobb角、手术节段Cobb角、C2-7矢状位轴向距离、胸廓入口角、胸1倾斜角、颈部倾斜角),分析邻近节段退变与颈椎矢状位参数的相关性。[结果] 随访期间出现31例邻近节段退变,45例无退变者。对两组的性别、年龄等基线比较,差异无统计学意义(P>0.05)。对术前两组患者之间的C2-7Cobb角、手术节段Cobb角、C2-7SVA、TIA、T1S、NT、T1S<19.5°等参数进行比较,差异均无统计学意义(P>0.05)。术后退变组的C2-7Cobb角、手术节段Cobb角、T1S均小于无退变组,差异均具有统计学意义(P<0.05);术后两组患者之间C2-7SVA、TIA和NT的差异均无统计学意义(P>0.05)。此外,术后退变组中T1S<19.5°的患者比例明显高于无退变组,差异具有统计学意义(P<0.05)。[结论] 颈椎前路单节段椎间盘切除融合术后邻近节段退变与颈椎矢状位参数密切相关,手术节段Cobb角恢复不良导致C2-7Cobb角的丧失,进而引起颈椎矢状位失衡是引起ACDF术后发生ASD的原因之一。

    Abstract:

    [Objective]To investigate the correlation between adjacent segment degeneration and cervical sagittal parameters after anterior cervical discectomy and fusion.[Methods]Retrospective analysis of 76 patients with cervical spondylotic myelopathy who underwent cervical anterior segmental single-segment discectomy and fusion (ACDF) surgery from January 2012 to December 2017 with complete follow-up data. Data were divided into degenerative and non-degenerate groups based on whether adjacent segment degeneration occurred during follow-up. The general data (sex, age, body mass index, etc.) and cervical sagittal parameters (C2-7 Cobb angle, surgical segment Cobb angle, C2-7 sagittal vertical axis, thoracic inlet angle, T1 slope, neck tilt).The correlation between adjacent segment degeneration and sagittal parameters of the cervical spine was analyzed.[Results]During the follow-up period, 31 cases of adjacent segment degeneration occurred, and 45 cases had no degeneration. There was no significant difference in the baseline sex and age between the two groups (P>0.05).The parameters of C2-7Cobb angle, surgical segment Cobb angle, C2-7SVA, TIA, T1S, NT, T1S<19.5° between the two groups were not statistically significant (P>0.05).The C2-7Cobb angle, surgical segment Cobb angle and T1S in the postoperative degenerative group were lower than those in the non-degeneration group, and the differences were statistically significant (P<0.05).There were no significant differences in C2-7SVA, TIA and NT between the two groups (P>0.05).In addition, the proportion of patients with T1S<19.5°in the postoperative degeneration group was significantly higher than that in the non-degeneration group, and the difference was statistically significant (P<0.05).[Conclusions]The adjacent segment degeneration after anterior cervical discectomy and fusion is closely related to the sagittal parameters of cervical vertebra. Poor recovery of Cobb Angle at the surgical segment resulted in the loss of C2-7cobb Angle, which further led to cervical sagittal imbalance, which was one of the causes of ASD after ACDF.

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  • 收稿日期:2019-08-12
  • 最后修改日期:2019-08-15
  • 录用日期:2019-09-12
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