Objective:To investigate the clinical value of posterior percutaneous endoscopic decompression (PED) in the treatment of single-segment cervical spondylotic myelopathy (CSM).Methods:Clinical data of 21 patients with single-segment cervical spondylotic myelopathy who underwent posterior cervical percutaneous large-channel endoscopic (DELTA) decompression and completed regular follow-up were performed from February 2016 to March 2018, including 13males and 8 females. ages 30-81 years, mean 49.5 years, follow-up 6 months postoperative, collect surgical information (surgery time, bleeding volume, hospital stay, complications, etc.), according to the Japan Orthopedic Association (JOA) score and Pain visual analogue scale (VAS),the surgical outcome was evaluated. Cervical spine X-ray was used to evaluate cervical curvature (CSA,C2-7Cobb angle). CT and MRI were used to observe laminectomy and nerve root decompression. MRI was used to observe the signal changes of spinal cord and posterior cervical muscles .JOA score, VAS score, cervical curvature (CSA,C2-7Cobb angle) were statistically analyzed, and the clinical outcome was evaluated by modified Macnab criteria at the last follow-up. Results:The JOA and VAS scores were compared between the time points (1 day pre-op, 3 days,3 months and6 months post-op, ). The difference was statistically significant (P<0.05). There were no significant differences in cervical curvature (CSA,C2-7Cobb angle) between the time points (1 day pre-op, 1 week ,3 months and 6 months post-op) (P>0.05). The operation time was 45-110 min, mean (68.6±23.8) min; the intraoperative blood loss was 20-85 ml, mean (28±14.8) ml, and the hospital stay was 3-8 days ,mean 4.5 days. At the last follow-up, the clinical efficacy was evaluated by modified Macnab criteria. The results were excellent in 12 cases, good in 7 cases, and fair in 2 cases. The excellent and good rate was 90.47%. Postoperative CT and MRI showed compression of the spinal cord and nerve root. Conclusion:Endoscopic decompression of posterior cervical vertebrae is a safe, feasible and effective surgical method with minimal invasive, with effective and rapid recovery.